Keyboard shortcut to close a window

Lets say you are in the final stages of working on a document and you have made the final edits.  You want to save the document and close the window.  If your hands are on the keyboard what’s the quickest way of doing this?  Saving is easy enough as you can use Ctrl+S.

But how do you close the window without clicking on the Close button?  Just press Alt+F4.  Alt+F4 closes the current window.

 

Any questions, please let me know.